NYU Dataset
Immunotherapy Efficacy in Melanoma is Modulated by Gut Microbiota
UID: 10488
- Description
This study characterized gut microbiome in pre-treatment stool using 16S rRNA gene and shotgun metagenome sequencing in melanoma patients undergoing immunotherapy. Transcriptional expression of metagenomic pathways was confirmed with metatranscriptome sequencing. They also examined associations of taxa and metagenomic pathways with progression-free survival (PFS). This dataset contains 16S rRNA gene and shotgun metagenome sequencing data. The publication also has supplementary data, which includes data about alpha and beta diversity in relation to PFS, genera, species, sub-operational taxonomic units (s-OTUs), and subspecies, metagenome MetaCyc functional pathways, metagenome MetaCyc reactions, and UniRef90 gene families.
- Timeframe
- 2016 - 2018
- Geographic Coverage
-
New York (State) - New York City
Access
- Restrictions
-
Free to All
- Instructions
- The data supporting the conclusions of this article are available in the Sequence Read Archive (SRA) through BioProject. All other data are provided in the paper on PubMed Central (PMC) under Supplementary Materials.
Observational
- Grant Support
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