The National Health and Nutrition Examination Survey (NHANES) is a program of studies designed to assess the health and nutritional status of adults and children in the United States. An ongoing annual survey combines interviews and physical examinations. The NHANES interview includes demographic, socioeconomic, dietary, and health-related questions. The examination component consists of medical, dental,...

Project Tycho includes data from all weekly notifiable disease reports for the United States and elsewhere dating back to 1888. It includes data counts for 58 diseases and 92 conditions; the availability of data varies by condition and location. Data are available as pre-compiled datasets, through a data query system, and through an API. Pre-compiled datasets include 92 datasets on specific diseases...

The New York City Department of Health and Mental Hygiene (NYC DOHMH) has shared vital statistics data (birth and mortality data) online. Birth data includes demographic information on the mother, including age, race, and education. Mortality data includes demographic information on the deceased, such as age, sex, race, and education. The publicly-available birth and death micro-SAS datasets provide...

The Surveillance, Epidemiology, and End Results (SEER) Program at the National Cancer Institute (NCI) is the authoritative source of information on cancer incidence and survival in the United States. SEER collects data on cancer incidence and population data associated by age, sex, race, year of diagnosis, and geographic area from registries across the country, covering approximately 48% of the national...

The Demographic and Health Surveys (DHS) Program overseen by the US Agency for International AID (USAID) uses nationally representative surveys, biomarker testing, and geographic location to collect data on monitoring and impact evaluation indicators for individual countries and for cross-country comparisons. Standardized DHS surveys include the Demographic and Health Survey, Service Provision Assessment,...

The Youth Risk Behavior Surveillance System (YRBSS) collects information about six types of health-risk behaviors that contribute to the leading causes of death and disability among youth and adults in the United States, including: (1) Behaviors that contribute to unintentional injuries and violence; (2) Sexual behaviors related to unintended pregnancy and sexually transmitting diseases, including...

The NYU Alzheimer’s Disease Research Center (NYU ADRC) maintains a large database of standardized clinical and neuropathological research data collected at NYU Langone Health for local investigators, as well as those at affiliated or collaborating institutions. The NYU ADRC database includes a cumulative record of over 1,500 subjects enrolled since 1972. Data was collected every two years until 2005...

The National Center for Advancing Translational Sciences (NCATS) has systematically compiled clinical, laboratory and diagnostic data from electronic health records to support COVID-19 research efforts via the National COVID Cohort Collaborative (N3C) Data Enclave. As of August 2, 2022, the repository contains information from over 15 million patients (including 5.8 million COVID-19 positive patients)...

The Prostate, Lung, Colorectal, and Ovarian (PLCO) Cancer Screening Trial was a large randomized controlled trial that assessed whether certain screening practices decreased deaths from prostate, lung, colorectal and ovarian cancer. Approximately 155,000 men and women aged 55 to 74 years old were enrolled from 10 screening centers across the United States between November 1993 and July 2001. Participants...

This dataset from the North American SUDEP Registry represents an ongoing collaborative effort to collect clinical information, tissue, and DNA to support research on clinical research factors for Sudden Unexpected Death in Epilepsy (SUDEP) and other causes of epilepsy-related deaths. For enrollment in the registry, at least one of the following criteria was satisfied: SUDEP within the last five...