NYU Data Catalog

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Results Found: 5

  • Alzheimer’s Disease Neuroimaging Initiative

    Alternate Title(s)
    ADNI, ADNI1, ADNI GO, ADNI2, ADNI3
    Authors
    Michael W. Weiner
    Description

    The Alzheimer’s Disease Neuroimaging Initiative (ADNI) began in 2004 as longitudinal multicenter study to identify clinical, imaging, genetic, and biochemical biomarkers for the detection and tracking of Alzheimer’s disease (AD). Participants are recruited from and followed at 59 research sites in the United States and Canada. ADNI1 enrolled 400 subjects who were diagnosed with mild cognitive impairment...

    Subject
    Chronic Disease
    Genomics
    Mental Health
    Neuroscience
    Access Rights
    Free to All
    Application Required
    Author Approval Required
    Local Expert
    Omonigho M. Bubu
    Ricardo Osorio

  • National Alzheimer’s Coordinating Center Data

    Alternate Title(s)
    NACC
    Description

    The National Alzheimer’s Coordinating Center (NACC) was created in 1999 to facilitate research with data collected from Alzheimer's Disease Research Centers (ADRCs) across the United States. NACC oversees data collection and sharing for a number of datasets. The Uniform Data Set (UDS) contains longitudinal and standardized data collected from ADRCs since 2005. ADRC enrollment protocols vary and...

    Subject
    Chronic Disease
    Mental Health
    Neuroscience
    Access Rights
    Free to All
    Application Required
    Author Approval Required
    Local Expert
    Omonigho M. Bubu
    Ricardo Osorio
  • NYU Dataset

    Predictors of Neuritic Plaque and Neurofibrillary Tangle Pathology Determined From Rush Religious Orders Study

    Authors
    Stephen D. Ginsberg
    Michael H. Malek-Ahmadi
    Melissa J. Alldred
    Yinghua Chen
    4 more author(s)...
    Description

    This study investigated whether the Alzheimer’s disease (AD) pathological lesions diffuse plaques (DPs), neuritic plaques (NPs), and neurofibrillary tangles (NFTs). For this study, downregulation of brain-derived neurotrophic factor (BDNF) and its cognate neurotrophin receptor, TrkB, were observed during the progression of dementia. They performed negative binomial (NB) regressions using gene expression...

    Subject
    Neuroscience
    Access Rights
    Application Required
    Author Approval Required
  • NYU Dataset

    Selective Decline of Neurotrophin and Neurotrophin Receptor Genes Discovered From Rush Religious Orders Study

    Authors
    Stephen D. Ginsberg
    Michael H. Malek-Ahmadi
    Melissa J. Alldred
    Shaoli Che
    7 more author(s)...
    Description

    This study profiled neurotrophin and neurotrophin receptor gene expression within microdissected CA1 neurons along with regional hippocampal dissections from participants in the Rush Religious Orders Study (RROS). The RROS participants included older religious clergy who have agreed to medical and psychological evaluation each year and brain donation after death. This study began in 1993 and has enrolled...

    Subject
    Neuroscience
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    Application Required
    Author Approval Required
  • NYU Dataset

    Interictal Epileptiform Discharges Affect Memory in an Alzheimer’s Disease

    Authors
    Marisol Soula
    Anna Maslarova
    Ryan E. Harvey
    Manuel Valero
    4 more author(s)...
    Description

    This study compared the interictal epileptiform discharges (IEDs) of human epilepsy patients from microwire hippocampal recording with those of Alzheimer’s disease (AD) transgenic mice with implanted multilayer hippocampal silicon probes. They investigated the local field potential properties of human IEDs recorded from mesial temporal lobe structures of patients with drug-resistant frontal and temporal...

    Subject
    Neuroscience
    Access Rights
    Free to All