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NYU Dataset
Biomimetic Extracellular Matrix Nanofibers Electrospun with Calreticulin Promote Synergistic Activity for Tissue Regeneration
- Authors
- Mary E. StackSarita MishraMatangi Parimala Chelvi RatnamaniHaoyu Wang2 more author(s)...
- Description
Previous studies showed the potential of calreticulin (CRT) protein in enhancing the rate and quality of wound healing in excisional animal wound models. This study determined if polycaprolactone (PCL)/type 1 collagen (Col1) nanofibers (NFs) could be used as an effective carrier for CRT while at the same time introducing further wound healing capability through the synergy of biological and physicochemical...
- Subject
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Anatomy
- Access Rights
- Application RequiredAuthor Approval Required
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NYU Dataset
Calreticulin Accelerates Corneal Wound Closure and Mitigates Fibrosis
- Authors
- Sarita MishraMiguel A. ManzanaresJustin PraterDavid Culp1 more author(s)...
- Description
Previous studies demonstrated that topically applied calreticulin (CALR) healed full‐thickness excisional animal wounds by a tissue regenerative process markedly enhancing repair without evoking angiogenesis. This study applied CALR in a rabbit corneal injury model. They accelerated full wound closure by 3 days and delayed healing caused by corticosteroids by 6 days. In addition, healed wounds without...
- Subject
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Anatomy
- Access Rights
- Application RequiredAuthor Approval Required