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NYU Dataset
Neural recordings from the visual cortex and the prearcuate gyrus of macaque monkeys
- Authors
- Ori MaozGasper TkacikMohamad Saleh EstekiRoozbeh Kiani1 more author(s)...
- Description
This data collection includes neural recordings obtained from the visual cortex (V1 and V2) and prearcurate gyrus (8Ar) of macaque monkeys (Macaca nemestrina and Macaca mulatta) during a direction discrimination task and code for replicating the modeling of neural representations. 96-channel microelectrode Utah arrays were implanted across the border of the V1 and V2 visual cortices of Macaca nemestrina....
- Subject
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Neuroscience
- Access Rights
- Free to All
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NYU Dataset
GABA Decrease is Associated With Degraded Neural Specificity in the Visual Cortex of Glaucoma Patients
- Authors
- Ji Won BangCarlos ParraKevin YuGadi Wollstein2 more author(s)...
- Description
To investigate the GABAergic and glutamatergic systems and neural specificity in the visual cortex of glaucoma patients, the research team recruited 40 patients with glaucoma (14 with early glaucoma and 16 with advanced glaucoma) and 24 age-matched healthy subjects to undergo clinical ophthalmic exams and magnetic resonance imaging (MRI) with fixation tasks. Researchers obtained the following data: Structural...
- Subject
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AnatomyChronic DiseaseNeuroscience
- Access Rights
- Free to All
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NYU Dataset
Forty-Hertz Light Stimulation Does Not Entrain Native Gamma Oscillations in Alzheimer’s Disease
- Authors
- Marisol SoulaAlejandro Martin-AvilaYiyao ZhangAnnika Dhingra4 more author(s)...
- Description
Alzheimer’s disease (AD) is characterized by abnormal aggregation of the proteins amyloid-β (Aβ). Recent studies showed that 40-Hz sensory stimulation is a potential treatment in AD. This study examined whether 40-Hz flickering light entrains gamma oscillations and suppresses Aβ in the brains of APP/PS1 and 5xFAD mouse models. For the study, they investigated the effect of 40-Hz light stimulation on...
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Neuroscience
- Access Rights
- Free to All
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NYU Dataset
Impairment of Visual Cortical Plasticity by Amyloid-Beta Species
- Authors
- Christopher M. WilliamMatthew A. SternXuewei PeiLubna Saqran3 more author(s)...
- Description
Alzheimer’s disease (AD) is characterized by accumulation of amyloid-beta (Aβ) in amyloid plaques and transgenic and knock-in mice that express mutant alleles of amyloid precursor protein (APP) have been used to model the effects of Aβ. This study examined visual system plasticity in transgenic mice that express and secrete Aβ throughout the brain in the absence of APP overexpression to explore the...
- Subject
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Neuroscience
- Access Rights
- Application RequiredAuthor Approval Required
