NYU Data Catalog

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  • NYU Dataset

    Unique dynamics and exocytosis properties of GABAergic synaptic vesicles revealed by three-dimensional single vesicle tracking

    Authors
    Chungwon Park
    Xingxiang Chen
    Chong-Li Tian
    Gyu Nam Park
    7 more author(s)...
    Description

    This dataset contains x, y, and z trajectories of single GABAergic synaptic vesicles that we obtained by labelling GABAergic synaptic vesicles with streptavidin-coated QDs to commercially available biotinylated antibodies against the luminal domain of the vesicular GABA transporter (VGAT) and tracking the real-time three-dimensional position of single GABAergic synaptic vesicles up to the moment of...

    Subject
    Neuroscience
    Access Rights
    Free to All
  • NYU Dataset

    Synaptic Vesicle Traffic is Supported by Transient Actin Filaments

    Authors
    Nicolas Chenouard
    Feng Xuan
    Richard W. Tsien
    Description

    Synaptic vesicles (SVs) play a key role in synaptic transmission. This study used time-lapse microscopy to demonstrate two distinct mechanisms of vesicle traffic along axons. They utilized specific pharmacological interventions along with imaging of transient actin polymerization, and traffic of recycling SVs loaded with single quantum dots to characterize the underlying axonal actin structures. For...

    Subject
    Neuroscience
    Access Rights
    Application Required
    Author Approval Required