NYU Dataset
Synaptic Vesicle Traffic is Supported by Transient Actin Filaments
Part of: Oxytocin U19 BRAIN Initiative |
Part of: Tsien Lab |
UID: 10561
- Description
Synaptic vesicles (SVs) play a key role in synaptic transmission. This study used time-lapse microscopy to demonstrate two distinct mechanisms of vesicle traffic along axons. They employed specific pharmacological interventions along with imaging of transient actin polymerization and traffic of recycling SVs loaded with single quantum dots to characterize the underlying axonal actin structures. For the study, hippocampal neurons were cultured from postnatal day 0 male and female Sprague Dawley rat pups. The dataset contains time-lapse imaging of vesicle traffic and actin polymerization, and immunocytochemistry data.
Access
- Restrictions
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- Instructions
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