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  • NYU Dataset

    Cell Type-Specific Membrane Potential Changes in Dorsolateral Striatum Accompanying Reward-Based Sensorimotor Learning

    Authors
    Tanya Sippy
    Corryn Chaimowitz
    Sylvain Crochet
    Carl C.H. Petersen
    Description

    This study examined changes in membrane potential dynamics of dorsolateral striatal neurons comparing naive mice and expert mice trained to lick a reward spout in response to whisker deflection. In the study, the mice were implanted with a light-weight metal head-post and a recording chamber. The position of the DLS was stereotaxically marked at the surface of the skull and the animals were returned...

    Subject
    Neuroscience
    Access Rights
    Free to All
  • NYU Dataset

    Transformation of Primary Sensory Cortical Representations From Layer 4 to Layer 2

    Authors
    Bettina Voelcker
    Ravi Pancholi
    Simon Peron
    Description

    Sensory input arrives from thalamus in cortical layer (L) 4 and L4 to L2 constitutes one of the earliest cortical feedforward networks. However, the transformation performed by this network remains unknown. This study used two-photon calcium imaging to record neural activity in L2 to L4 of primary vibrissal somatosensory cortex (vS1) as mice perform an object localization task with two whiskers. To...

    Subject
    Neuroscience
    Access Rights
    Free to All