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  • Multicenter Osteoarthritis Study

    Alternate Title(s)
    MOST
    Authors
    Neil A. Segal
    Michael C. Nevitt
    K. Douglas Gross
    Jean Hietpas
    3 more author(s)...
    Description

    The Multicenter Osteoarthritis Study (MOST) is an ongoing longitudinal study which aims to identify novel and modifiable biomechanical factors (e.g., physical activity), bone and joint structural factors (assessed through knee MRI), and nutritional factors that are associated with the onset and progression of osteoarthritis (OA)-related knee symptoms and radiographic knee OA. A secondary aim is to...

    Subject
    Chronic Disease
    Risk Factors
    Access Rights
    Application Required
    Author Approval Required
    Local Expert
    Cem Deniz
  • NYU Dataset

    Ca2+ Channel ORAI1 Regulates Oral Cancer Growth and Nociceptive Pain

    Authors
    Ga-Yeon Son
    Nguyen Huu Tu
    Maria Daniela Santi
    Santiago Loya Lopez
    9 more author(s)...
    Description

    This study described the function of the Ca2+ channel ORAI1 as an important regulator of oral cancer pain. Previous study showed that ORAI1 was highly expressed in tumor samples from patients with oral cancer. ORAI1 activation caused sustained Ca2+ influx in human oral cancer cells. They analyzed the expression of ORAI1 in the human oral squamous cell carcinoma cell lines HSC-3 and SCC-9, in the dysplastic...

    Subject
    Cancer
    Genomics
    Access Rights
    Free to All