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  • NYU Dataset

    Oxytocin Alters Intrinsic Properties of CA2 Pyramidal Cells to Induce Burst Firing

    Authors
    Natasha N. Tirko
    Katherine W. Eyring
    Ioana Carcea
    Mariela Mitre
    3 more author(s)...
    Description

    This study described robust oxytocinergic modulation of intrinsic properties and circuit operations in hippocampal area CA2. For this study, male mice were used for all experiments to avoid variation in oxytocin receptor (OXTR) expression throughout the estrous cycle of female mice. C57BL/6 mice were used in wild-type experiments, while homozygous Oxt-IRES-Cre and hemizygote Amigo2-Cre mice were used...

    Subject
    Neuroscience
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  • NYU Dataset

    Oxytocin Induces Embryonic Diapause in Mice

    Authors
    Jessica L. Minder
    Sarah B. Winokur
    Janaye Stephens
    Jie Tong
    14 more author(s)...
    Description

    This study demonstrate that oxytocin induces diapause, a temporary developmental delay, in pre-implantation mouse embryos to help ensure their survival. To assess whether oxytocin receptor (OXTR) signaling might influence this gestational delay, heterozygous (OXTR+/−) dams were bred, which retain sufficient OXTR function for apparently normal parturition and nursing. After the second breeding, these...

    Subject
    Neuroscience
    Access Rights
    Free to All