-
NYU Dataset
Limited Environmental Serine and Glycine Confer Brain Metastasis Sensitivity to PHGDH Inhibition
- Authors
- Bryan NgoEugenie KimVictoria Osorio-VasquezSophia Doll36 more author(s)...
- Description
Brain metastasis is the most common intracranial malignancy in adults, which is often fatal. Studies have shown that brain metastases depend on cooperative cellular interactions between tumor cells and specialized cells within the central nervous system (CNS). Metabolic constraints imposed by the serine and glycine limited brain environment restrict metastatic tumor growth. This study showed that 3-phosphoglycerate...
- Subject
-
NeuroscienceProteomics
- Access Rights
- Application RequiredAuthor Approval Required
-
NYU Dataset
NYUMets
- Alternate Title(s)
- NYUMets_Brain v1.0
- Authors
- Douglas KondziolkaEric K. OermannKatherine E. Link
- Description
NYUMets is a repository of imaging and clinical data contributed by patients participating in the Center for Advanced Radiosurgery clinical registry with stage IV (metastatic) brain cancer. The first data release, NYUMets_Brain v1.0, contains over 20,000 de-identified and anonymized image sequences from 8,003 MRI studies and associated clinical data collected from 1,429 patients. Each patient contributed...
- Subject
-
AnatomyCancerChronic DiseaseNeuroscience
- Access Rights
- Free to AllApplication Required
