NYU Data Catalog

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  • NYU Dataset

    Cell Type-Specific Membrane Potential Changes in Dorsolateral Striatum Accompanying Reward-Based Sensorimotor Learning

    Authors
    Tanya Sippy
    Corryn Chaimowitz
    Sylvain Crochet
    Carl C.H. Petersen
    Description

    This study examined changes in membrane potential dynamics of dorsolateral striatal neurons comparing naive mice and expert mice trained to lick a reward spout in response to whisker deflection. In the study, the mice were implanted with a light-weight metal head-post and a recording chamber. The position of the DLS was stereotaxically marked at the surface of the skull and the animals were returned...

    Subject
    Neuroscience
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  • NYU Dataset

    Energy Coupling and Stoichiometry of Zn2+/H+ Antiport by YiiP

    Authors
    Adel Hussein
    Shujie Fan
    Maria Lopez-Redondo
    Ian Kenney
    3 more author(s)...
    Description

    Previous studies of YiiP, bacterial Zn2+/H+ antiporter, have shown a homodimeric architecture and the presence of three distinct Zn2+ binding sites. YiiP is a representative of the cation diffusion facilitator superfamily, which are responsible for homeostasis of transition metal ions. This study used cryo-electron microscopy, microscale thermophoresis, and molecular dynamics simulations to address...

    Subject
    Proteomics
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