Filter by
-
Action to Control Cardiovascular Risk in Diabetes Trial
- Alternate Title(s)
- ACCORD
- Description
Action to Control Cardiovascular Risk in Diabetes (ACCORD) was a large clinical trial examining methods of lowering the rate of cardiovascular disease in adults with type two diabetes. The study was composed of three main clinical trials: an intensive lowering of blood sugar levels (Glycemia Trial), intensive lowering of blood pressure (Blood Pressure Trial), and treatment of multiple blood lipids...
- Subject
-
Chronic Disease
- Access Rights
- Application Required
- Local Expert
- Lois Katz
-
NYU Dataset
DIAPH1 Mediates Progression of Atherosclerosis and Regulates Hepatic Lipid Metabolism in Mice
- Authors
- Laura SenatusLander Egana-GorronoRaquel Lopez-DiezSonia Bergaya17 more author(s)...
- Description
Previous study indicated that the receptor for advanced glycation end products (RAGE) in the progression and regression of atherosclerosis. Therefore, this study examined if Diaphanous 1 (DIAPH1) binds to the RAGE cytoplasmic domain and contributes to progression of atherosclerosis. They intercrossed atherosclerosis prone Ldlr−/− mice with mice devoid of Diaph1 and fed them Western diet for 16 weeks....
- Subject
-
Genomics
- Access Rights
- Free to All