NYU Data Catalog

NYU Dataset

Authors: Sam McKenzie

Roman Huszar

Daniel F. English

Kanghwan Kim

3 more author(s)...
Description: This study examined how incorporation of synthetic hippocampal signals is constrained by pre-existing circuit dynamics. For this study, they optogenetically stimulated small groups of CA1 neurons as mice traversed a chosen segment of a linear track, which mimicked the emergence of place fields. Mice were trained to run laps on a linear track to retrieve water reward at each end. Before implantation,...
Subject: Neuroscience
Access Rights: Free to All

NYU Dataset

Authors: Laura Green

David Tingley

John Rinzel

Gyorgy Buzsaki
Description: Hippocampus plays a key role in navigation guided by environmental inputs. However, a critical aspect of navigation is a sequence of planned and coordinated actions. This study investigated the role of action in the neuronal organization of the hippocampus by training rats to jump a gap on a linear track. For this study, Long-Evans rats were used for recording local field potentials and ensembles of...
Subject: Neuroscience
Access Rights: Free to All

NYU Dataset

Authors: Asako Noguchi

Roman Huszar

Shota Morikawa

Gyorgy Buzsaki

1 more author(s)...
Description: Spike sequences are exemplified by memory replays in sharp-wave ripples (SWRs) and high-frequency oscillations resulting from pyramidal cell-interneuron interactions in the hippocampus. However, the microcircuitry mechanism that enables such flexible spike sequencing remains unknown. This study recorded the membrane potentials of multiple hippocampal CA1 pyramidal cells in mice. For this study, whole-cell...
Subject: Neuroscience
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NYU Dataset

Authors: Roland Zemla

Jason J. Moore

Maya D. Hopkins

Jayeeta Basu
Description: Hippocampal activity supports internal representation of learned experiences and contexts, which allows individuals to form long-term memories. This study investigated hippocampal maps formed under structured attention with learning rules stabilize and maintain task-selectivity during memory recall. They used longitudinal two-photon imaging of hundreds of hippocampal CA1 pyramidal neurons while mice...
Subject: Neuroscience
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NYU Dataset

Authors: Wannan Yang

Chen Sun

Roman Huszar

Thomas Hainmueller

1 more author(s)...
Description: Experiences need to be labeled during learning for further consolidation, but brain mechanisms that select experiences for lasting memory are unknown. This study determined that successive traversals in the maze were tracked by continuously drifting populations of neurons by combining large-scale neural recordings with a novel application of dimensionality reduction techniques. They recorded from many...
Subject: Neuroscience
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NYU Dataset

Authors: Michele N. Insanally

Badr F. Albanna

Jade Toth

Brian DePasquale

6 more author(s)...
Description: This study investigated the synaptic basis for various types of spiking response profiles, and how synaptic plasticity learning rules are important for shaping synaptic inputs for spike output and network performance. They leveraged cell-attached, extracellular, and whole-cell recordings from behaving animals alongside recurrent network modeling to explore the synaptic origins and functional contribution...
Subject: Neuroscience
Access Rights: Free to All