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NYU Dataset
Gene Expression and Transcription Factors are Modified in Human Keratinocytes Exposed to Solar Simulated Ultraviolet Radiation
- Authors
- Thomas L. Des MaraisThomas KluzDazhong XuXiaoru Zhang4 more author(s)...
- Description
Ultraviolet radiation (UVR) from the sun is the major cause of skin cancer. However, genes and pathways altered by solar-simulated UVR (ssUVR), a mixture of UVA and UVB, still remains unclear. For this study, human HaCaT keratinocytes were exposed to a single dose or 5 repetitive doses of ssUVR. Analyses of gene expression profiles and functional annotation were performed at 24 hours after irradiation....
- Subject
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CancerGenomics
- Access Rights
- Free to All
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NYU Dataset
Biomimetic Extracellular Matrix Nanofibers Electrospun with Calreticulin Promote Synergistic Activity for Tissue Regeneration
- Authors
- Mary E. StackSarita MishraMatangi Parimala Chelvi RatnamaniHaoyu Wang2 more author(s)...
- Description
Previous studies showed the potential of calreticulin (CRT) protein in enhancing the rate and quality of wound healing in excisional animal wound models. This study determined if polycaprolactone (PCL)/type 1 collagen (Col1) nanofibers (NFs) could be used as an effective carrier for CRT while at the same time introducing further wound healing capability through the synergy of biological and physicochemical...
- Subject
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Anatomy
- Access Rights
- Application RequiredAuthor Approval Required