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  • NYU Dataset

    Gene Expression and Transcription Factors are Modified in Human Keratinocytes Exposed to Solar Simulated Ultraviolet Radiation

    Authors
    Thomas L. Des Marais
    Thomas Kluz
    Dazhong Xu
    Xiaoru Zhang
    4 more author(s)...
    Description

    Ultraviolet radiation (UVR) from the sun is the major cause of skin cancer. However, genes and pathways altered by solar-simulated UVR (ssUVR), a mixture of UVA and UVB, still remains unclear. For this study, human HaCaT keratinocytes were exposed to a single dose or 5 repetitive doses of ssUVR. Analyses of gene expression profiles and functional annotation were performed at 24 hours after irradiation....

    Subject
    Cancer
    Genomics
    Access Rights
    Free to All
  • NYU Dataset

    Biomimetic Extracellular Matrix Nanofibers Electrospun with Calreticulin Promote Synergistic Activity for Tissue Regeneration

    Authors
    Mary E. Stack
    Sarita Mishra
    Matangi Parimala Chelvi Ratnamani
    Haoyu Wang
    2 more author(s)...
    Description

    Previous studies showed the potential of calreticulin (CRT) protein in enhancing the rate and quality of wound healing in excisional animal wound models. This study determined if polycaprolactone (PCL)/type 1 collagen (Col1) nanofibers (NFs) could be used as an effective carrier for CRT while at the same time introducing further wound healing capability through the synergy of biological and physicochemical...

    Subject
    Anatomy
    Access Rights
    Application Required
    Author Approval Required