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T1D Exchange Clinic Registry
- Alternate Title(s)
- Type 1 Diabetes Exchange Registry
- Description
The Type 1 Diabetes (T1D) Exchange Clinic Registry collects information on individuals with type 1 diabetes from participating institutions in the United States in order to help researchers characterize individuals living with the disease, conduct exploratory or hypothesis-generating analyses, and identify potential participants for future clinical studies. The registry includes over 26,000 individuals...
- Subject
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Chronic DiseaseHealth StatusPopulation Characteristics
- Access Rights
- Free to AllApplication Required
- Local Expert
- Jeniece IlkowitzMargaret McCarthy
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NYU Dataset
Brain Insulin Resistance in Subjects with Major Depressive Disorder
- Authors
- Carla NascaJosh DobbinBenedetta BigioKathleen Watson9 more author(s)...
- Description
Previous studies in rodent showed impaired brain insulin signaling with resultant insulin resistance (IR) modulates synaptic plasticity and the corresponding behavioral functions. This study investigated whether brain enriched exosomes and brain IR differ between subjects with major depressive disorder (MDD) and respective controls. They also examined potential sex differences in circulating brain...
- Subject
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Neurosciences
- Access Rights
- Application RequiredAuthor Approval Required
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NYU Dataset
Acetyl-L-Carnitine Deficiency in Patients with Major Depressive Disorder
- Authors
- Carla NascaBenedetta BigioFrancis S. LeeSarah P. Young9 more author(s)...
- Description
This study identified biological targets in major depressive disorder (MDD). Acetyl-l-carnitine (LAC), which is critical for hippocampal function and several behavioral domains, has rapid and enduring antidepressant like effects in LAC deficient rodents. As a result, this study examined LAC levels in humans. Following an initial phone screen, potential participants were evaluated in person to determine...
- Subject
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Neurosciences
- Access Rights
- Application RequiredAuthor Approval Required
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NYU Dataset
Insulin Signal Is Required for Sensory Neuron Development in Caenorhabditis elegans
- Authors
- Lauren Bayer HorowitzJulia P. BrandtNiels Ringstad
- Description
Caenorhabditis elegans (C. elegans) is a powerful model for the study of nervous system development. This study investigated mechanisms required for the development of C. elegans sensory neurons, BAGs. C. elegans express many insulin-like peptides (ILPs), which are released from BAGs, throughout the nervous system. It is found that the p38 MAP kinase PMK-3 that is required for the differentiation of...
- Subject
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GenomicsNeurosciences
- Access Rights
- Free to All