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  • NYU Dataset

    Staphylococcus Aureus Cell Envelope Selectively Controls the Sorting of Selective Exoproteins

    Authors
    Xuhui Zheng
    Gerben Marsman
    Keenan A. Lacey
    Jessica R. Chapman
    3 more author(s)...
    Description

    Leukocidins are crucial components of Staphylococcus aureus (S. aureus) and they are secreted toxins that directly target and lyse immune cells. One of the leukocidins, Leukocidin AB (LukAB), is associated with the bacterial cell envelope. This study examined how S. aureus regulates LukAB secretion as well as the role of bacteria-associated LukAB in host-pathogen interaction. Using tissue culture models...

    Subject
    Proteomics
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    Free to All
  • NYU Dataset

    RNA Sequencing Analysis of Caenorhabditis elegans DAF-18 During Primordial Germ Cell Quiescence

    Authors
    Amanda L. Fry
    Amy K. Webster
    Julia Burnett
    Rojin Chitrakar
    2 more author(s)...
    Description

    PTEN is one of the most frequently lost tumor suppressors in human cancers and regulates quiescence of stem cells and cancer cells. The Caenorhabditis elegans daf-18 gene encodes the worm version of PTEN. Previous studies showed that in worms that have lost daf-18 function, primordial germ cells (PGCs) inappropriately begin dividing in the L1 larvae hatched into starvation conditions. This study examined...

    Subject
    Genomics
    Access Rights
    Free to All