-
NYU Dataset
Data from Mucosal Immune Profiling in Patients with Inflammatory Bowel Disease
- Authors
- David P. HudesmanShannon ChangJordan E. Axelrad
- Description
This study dataset contains data from 28 adult and pediatric patients who were recruited from NYU Langone's Inflammatory Bowel Disease (IBD) Center. Study inclusion and exclusion criteria are noted below. Inclusion criteria: Subjects must have a suspected diagnosis of ulcerative colitis or Crohn’s disease Controls must have no clinical suspicion of ulcerative colitis or Crohn’s disease Signed and...
- Subject
-
Chronic DiseaseHealth StatusPopulation CharacteristicsRisk Factors
- Access Rights
- Application RequiredAuthor Approval Required
-
NYU Dataset
Immune Responses Observed Before and After BNT162b2 mRNA Vaccine Administration in Individuals with and without History of SARS-CoV-2 Infection
- Authors
- Marie I. SamanovicAmber R. CorneliusSophie L. Gray-GaillardJoseph Richard Allen7 more author(s)...
- Description
To study and compare longitudinal immune responses to two-dose BNT162b2 mRNA vaccinations, investigators recruited 15 adults with a history of laboratory-confirmed COVID-19 and 21 adults who did not have COVID-19. Participants' ages ranged from 21 to 65 years old. Peripheral immune responses were assessed via blood samples drawn before and after each vaccine dose. A total of five samples were collected...
- Subject
-
COVID-19Infectious Disease
- Timeframe
- 2021
- Access Rights
- Free to All
-
Bone marrow microenvironments that contribute to patient outcomes in newly diagnosed multiple myeloma
- Authors
- Samuel A. DanzigerMark McConnellJake GockleyMary H. Young29 more author(s)...
- Description
This dataset contains data on the tumor microenvironment from the whole bone marrow of 436 patients who were diagnosed with multiple myeloma and enrolled in the interventional Total Therapy trial series conducted by the University of Arkansas for Medical Sciences. 266 male and 170 female patients were enrolled between February 25, 2004 and January 11, 2014 and completed 25 to 5,241 days of follow-up...
- Subject
-
CancerChronic DiseaseGenomics
- Access Rights
- Free to All
- Local Expert
- Gareth J. Morgan
-
NYU Dataset
SARS-CoV-2 infection triggers pro-atherogenic inflammatory responses in human coronary vessels
- Authors
- Natalia EberhardtMaria G. NovalRavneet KaurLetizia Amadori19 more author(s)...
- Description
This study combined multiple techniques (e.g., RNAscope in-situ hybridization, immunohistochemistry, immunofluorescence, single-cell RNA sequencing, bulk RNA sequencing, and functional assays) to investigate the inflammatory response associated with SARS-CoV-2 infection in human vascular tissues. Single cell RNA-sequencing data obtained from samples collected for this study is available via the Gene...
- Subject
-
COVID-19Infectious DiseaseRisk Factors
- Access Rights
- Free to All
-
NYU Dataset
mRNA COVID-19 vaccine elicits potent adaptive immune response without the acute inflammation of SARS-CoV-2 infection
- Authors
- Ellie IvanovaJasmine ShwetarJoseph C. DevlinTerkild B. Buus17 more author(s)...
- Description
To investigate immune responses to SARS-CoV-2 antigens under various inflammatory conditions, researchers collected blood samples from five adult patients seen at NYU Langone Health with lab-confirmed cases of acute COVID-19 and from nine healthy adults (seven who had received the BNT162b2 mRNA vaccine and two with no prior exposure to SARS-CoV-2). Samples were obtained at multiple time points. Patients...
- Subject
-
COVID-19GenomicsInfectious Disease
- Access Rights
- Free to All
