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NYU Dataset
Condensed Mitochondria Assemble Into the Acrosomal Matrix During Spermiogenesis
- Authors
- Mindong RenYang XuColin K. L. PhoonHediye Erdjument-Bromage4 more author(s)...
- Description
Spermatogenesis prompts a series of striking changes in the intracellular composition and the spatial arrangement of organelles. Among those changes include alterations in the morphology of mitochondria. This study showed that condensed mitochondria are distinct organelles with a stable ultrastructure and a distinguishable proteome. To investigate the development of condensed mitochondria, they used...
- Subject
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Proteomics
- Access Rights
- Free to All
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NYU Dataset
RNA Sequencing Analysis of Caenorhabditis elegans DAF-18 During Primordial Germ Cell Quiescence
- Authors
- Amanda L. FryAmy K. WebsterJulia BurnettRojin Chitrakar2 more author(s)...
- Description
PTEN is one of the most frequently lost tumor suppressors in human cancers and regulates quiescence of stem cells and cancer cells. The Caenorhabditis elegans daf-18 gene encodes the worm version of PTEN. Previous studies showed that in worms that have lost daf-18 function, primordial germ cells (PGCs) inappropriately begin dividing in the L1 larvae hatched into starvation conditions. This study examined...
- Subject
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Genomics
- Access Rights
- Free to All
