NYU Data Catalog

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  • NYU Dataset

    Condensed Mitochondria Assemble Into the Acrosomal Matrix During Spermiogenesis

    Authors
    Mindong Ren
    Yang Xu
    Colin K. L. Phoon
    Hediye Erdjument-Bromage
    4 more author(s)...
    Description

    This study used proteomic analysis, respirometry, and electron microscopy to examine the development of condensed mitochondria. The dataset contains proteomic and imaging data. The data indicate that condensed mitochondria formed from orthodox mitochondria during meiosis in order to support the formation of the acrosomal matrix. Condensed mitochondria also respired more actively and contained more...

    Subject
    Proteomics
    Access Rights
    Free to All
  • NYU Dataset

    RNA Sequencing Analysis of Caenorhabditis elegans DAF-18 During Primordial Germ Cell Quiescence

    Authors
    Amanda L. Fry
    Amy K. Webster
    Julia Burnett
    Rojin Chitrakar
    2 more author(s)...
    Description

    PTEN is one of the most frequently lost tumor suppressors in human cancers and regulates quiescence of stem cells and cancer cells. The Caenorhabditis elegans daf-18 gene encodes the worm version of PTEN. Previous studies showed that in worms that have lost daf-18 function, primordial germ cells (PGCs) inappropriately begin dividing in the L1 larvae hatched into starvation conditions. This study examined...

    Subject
    Genomics
    Access Rights
    Free to All