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  • NYU Dataset

    Spatial Transcriptomics Stratifies Psoriatic Disease Severity

    Authors
    Rochelle L. Castillo
    Ikjot Sidhu
    Igor Dolgalev
    Tinyi Chu
    21 more author(s)...
    Description

    This study described human psoriasis (PsO), which is a prototypic immune-mediated condition with a high predilection for extra-cutaneous involvement. Although the cellular and molecular features of human inflammatory skin diseases have been identified, their tissue context and systemic impact remains unclear. Spatial transcriptomics was performed to explain the cellular landscape of both healthy and...

    Subject
    Genomics
    Access Rights
    Free to All
  • NYU Dataset

    Biomimetic Extracellular Matrix Nanofibers Electrospun with Calreticulin Promote Synergistic Activity for Tissue Regeneration

    Authors
    Mary E. Stack
    Sarita Mishra
    Matangi Parimala Chelvi Ratnamani
    Haoyu Wang
    2 more author(s)...
    Description

    Previous studies showed the potential of calreticulin (CRT) protein in enhancing the rate and quality of wound healing in excisional animal wound models. This study determined if polycaprolactone (PCL)/type 1 collagen (Col1) nanofibers (NFs) could be used as an effective carrier for CRT while at the same time introducing further wound healing capability through the synergy of biological and physicochemical...

    Subject
    Anatomy
    Access Rights
    Application Required
    Author Approval Required