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NYU Dataset
Bilateral Medial Entorhinal Cortex Silencing Causes Remapping in CA1 Cell Assemblies
- Authors
- Ipshita ZutshiManuel ValeroAntonio Fernandez-RuizGyorgy Buzsaki
- Description
The discovery of grid cells in the medial entorhinal cortex (mEC) encouraged investigation of the effect of the mEC on the hippocampus. Large lesions of the entorhinal cortex reduced theta oscillations, decreased the fraction of hippocampal CA1 place cells, and affected various features of place field properties. This study performed combined optogenetic and pharmacogenetic local and upstream inactivation...
- Subject
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Neuroscience
- Access Rights
- Free to All
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NYU Dataset
Lateral Entorhinal Cortex Inputs Modulate Hippocampal Dendritic Excitability
- Authors
- Olesia M. BilashSpyridon ChavlisCara D. JohnsonPanayiota Poirazi1 more author(s)...
- Description
Lateral entorhinal cortex (LEC) performs important functions for episodic memory processing and coding for contextually salient elements of an environment or experience. This study combined functional circuit mapping and computational modeling to examine the cellular and circuit mechanisms by which long-range glutamatergic LEC projections influence the local activity in the hippocampus. This dataset...
- Subject
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Neuroscience
- Access Rights
- Application RequiredAuthor Approval Required
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NYU Dataset
Working Memory Features Are Embedded in Hippocampal Place Fields
- Authors
- Viktor VargaPeter C. PetersenIpshita ZutshiRoman Huszar2 more author(s)...
- Description
Previous studies indicated that the fraction of splitter fields is affected by the delay between responses in a spatial alternation task. This study demonstrated that memory and place field features of both pyramidal cells and interneurons in the hippocampus are interchangeable. They trained two groups of mice with and without delays in one or two environments and examined firing characteristics of...
- Subject
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Neuroscience
- Access Rights
- Free to All
