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Results Found: 4
  • NYU Dataset

    Human Oral Microbiota Composition Data from UAE Healthy Future Study (UAEHFS) Pilot Participants

    Authors
    Yvonne Vallès
    Claire K. Inman
    Brandilyn A. Peters
    Raghib Ali
    24 more author(s)...
    Description

    This dataset includes 330 Emirati adults participating in the UAE Healthy Future Study-Pilot (UAEHFS-pilot) who provided mouthwash samples. There were 225 non-smokers and 105 smokers who used cigarettes, dokha, shisha, or a combination of tobacco products. 101 of the 105 smokers were male. Tobacco use and frequency were assessed with a structured questionnaire and urine cotinine lab results. Gene...

    Subject
    Health Status
    Risk Factors
    Access Rights
    Free to All
    Application Required
  • NYU Dataset

    Whole Exome Sequencing Confirmed Progression of Smoldering Multiple Myeloma to Multiple Myeloma

    Authors
    Eileen M. Boyle
    Shayu Deshpande
    Ruslana Tytarenko
    Cody Ashby
    19 more author(s)...
    Description

    Smoldering multiple myeloma (SMM) is an asymptomatic plasma cell disorder. It is associated with a high-risk of progression to multiple myeloma (MM). For this study, they performed targeted sequencing on 82 patients. The results showed fewer NRAS and FAM46C mutations with SMM, which is consistent with their role as drivers of the transition to MM. They also analyzed the change in clonal structure over...

    Subject
    Cancer
    Genomics
    Access Rights
    Free to All
    Author Approval Required
  • Generation R

    Authors
    Vincent W. V. Jaddoe
    Generation R Study Group
    Description

    Generation R is an ongoing prospective cohort study of child development from the prenatal period through young adulthood in a multi-ethnic population recruited from the Rotterdam, Netherlands metropolitan area. The study enrolled 9,778 mothers with a delivery date between April 2002 and January 2006; they had 9,749 live births. The primary objective of the study is to identify early environmental...

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    Author Approval Required
    Local Expert
    Akhgar Ghassabian
  • NYU Dataset

    NOGOB Receptor Deficiency Increases Cerebrovascular Permeability and Hemorrhage

    Authors
    Zhi Fang
    Xiaoran Sun
    Xiang Wang
    Ji Ma
    6 more author(s)...
    Description

    Cerebral cavernous malformation (CCM) lesions are caused by loss of function of CCM genes. Previous study showed that NOGOB receptor (NGBR) knockout in endothelial cells results in cerebrovascular lesions in the mouse embryo. However, the molecular mechanism by which NGBR regulates CCM1/2 expression has not been explained. This study used RNA sequencing analysis to determine the alteration of transcriptomic...

    Subject
    Genomics
    Access Rights
    Free to All