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NYU Dataset
Hyperactive CDK2 Activity in Basal-like Breast Cancer Imposes a Genome Integrity Liability
- Authors
- Vladislav O. SviderskiyLili BlumenbergElizabeth GorodetskyTriantafyllia Karakousi13 more author(s)...
- Description
This study showed that basal-like breast cancer (BLBC) is sensitive to suppression of iron-sulfur cluster (ISC) biosynthesis and identified DNA polymerase epsilon (POLE) as an ISC-containing protein that underlies this phenotype. This dataset includes RNA sequencing data and data underlying figures. The publication also contains supplementary data, which includes data for short hairpin RNA (shRNA)...
- Subject
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CancerGenomics
- Access Rights
- Free to All
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NYU Dataset
Human Hepatoma Huh-7 Cell Culture Models Deficient in Apolipoprotein B Secretion
- Authors
- Swati ValmikiSara RosarioAshley MooringChandana Prakashmurthy7 more author(s)...
- Description
Apolipoprotein B (apoB) is an essential structural protein for the assembly and secretion of triglyceride-rich lipoproteins. Inhibition of apoB and microsomal triglyceride transfer protein (MTP) decreases plasma lipid levels but at a risk of lipid accumulation in tissues. To understand the global consequences of APOB gene deficiency, a human hepatoma (Huh-7) cell culture model system deficient in apoB...
- Subject
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Genomics
- Access Rights
- Free to All