NYU Data Catalog

NYU Dataset

Alternate Title(s): NYU ADRC
Authors: Thomas Wisniewski
Description: The NYU Alzheimer’s Disease Research Center (NYU ADRC) maintains a large database of standardized clinical and neuropathological research data collected at NYU Langone Health for local investigators, as well as those at affiliated or collaborating institutions. The NYU ADRC database includes a cumulative record of over 1,500 subjects enrolled since 1972. Data was collected every two years until 2005...
Subject: Chronic Disease

Health Status

Mental Health

Neuroscience

Risk Factors
Access Rights: Application Required

NYU Dataset

Authors: Marie I. Samanovic

Amber R. Cornelius

Sophie L. Gray-Gaillard

Joseph Richard Allen

7 more author(s)...
Description: To study and compare longitudinal immune responses to two-dose BNT162b2 mRNA vaccinations, investigators recruited 15 adults with a history of laboratory-confirmed COVID-19 and 21 adults who did not have COVID-19. Participants' ages ranged from 21 to 65 years old. Peripheral immune responses were assessed via blood samples drawn before and after each vaccine dose. A total of five samples were collected...
Subject: COVID-19

Infectious Disease
Timeframe: 2021
Access Rights: Free to All

Alternate Title(s): MOST
Authors: Neil A. Segal

Michael C. Nevitt

K. Douglas Gross

Jean Hietpas

3 more author(s)...
Description: The Multicenter Osteoarthritis Study (MOST) is an ongoing longitudinal study which aims to identify novel and modifiable biomechanical factors (e.g., physical activity), bone and joint structural factors (assessed through knee MRI), and nutritional factors that are associated with the onset and progression of osteoarthritis (OA)-related knee symptoms and radiographic knee OA. A secondary aim is to...
Subject: Chronic Disease

Risk Factors
Access Rights: Application Required

Author Approval Required
Local Expert: Cem Deniz

NYU Dataset

Authors: Ellie Ivanova

Jasmine Shwetar

Joseph C. Devlin

Terkild B. Buus

17 more author(s)...
Description: To investigate immune responses to SARS-CoV-2 antigens under various inflammatory conditions, researchers collected blood samples from five adult patients seen at NYU Langone Health with lab-confirmed cases of acute COVID-19 and from nine healthy adults (seven who had received the BNT162b2 mRNA vaccine and two with no prior exposure to SARS-CoV-2). Samples were obtained at multiple time points. Patients...
Subject: COVID-19

Genomics

Infectious Disease
Access Rights: Free to All

NYU Dataset

Alternate Title(s): Vaccine‐generated Immunity in Ocrelizumab‐treated Patients: Longitudinal Assessments (VIOLA)
Authors: Ilya Kister

Ryan Curtin

Amanda L. Piquet

Tyler Borko

16 more author(s)...
Description: This is a prospective, two-year study of immunity against SARS-CoV-2 in multiple sclerosis patients receiving ocrelizumab (OCR) at the time of COVID vaccination. Researchers recruited 60 patients (aged 18-65) from the NYU MS Comprehensive Care Center in New York City and the Rocky Mountain MS Center at the University of Colorado Anschutz Medical Center in Aurora, CO. Participants provided blood samples...
Subject: Chronic Disease

COVID-19
Access Rights: Free to All

NYU Dataset

Authors: Sisi Chen

Rahul S. Vedula

Antonio Cuevas-Navarro

Bin Lu

23 more author(s)...
Description: This study demonstrated that loss of LZTR1, or leukemia-associated mutants in the LZTR1 substrate and RAS GTPase RIT1 that escape degradation, drives hematopoietic stem cell expansion and leukemia in vivo. For the study, genome-scale CRISPR/Cas9 screen performed in different variants of the TF-1 cell line genetically-modified to express mutant forms of RIT1 (M90I or F82C) or depleted in LZTR1 by CRISPR/Cas9,...
Subject: Cancer

Genomics
Access Rights: Free to All