Should We Emergently Revascularize Occluded Coronaries for Cardiogenic Shock Trial
Alternate Titles(s): SHOCK Trial
- Description
This dataset contains information from the Should We Emergently Revascularize Occluded Coronaries for Cardiogenic Shock (SHOCK) study, a randomized controlled trial of 302 patients with cardiogenic shock (CS) due to acute myocardial infarction (MI); 175 were treated in the United States, 66 in Canada, and 61 in other countries. Data collected between April 1993 and November 1998 from 30 sites and were entered into a structured database housed at NERI (now Carelon Research).
Participants were randomly assigned to emergency revascularization or initial medical stabilization. Information was collected on all aspects of the patient and their hospital stay, including demographics (race, ethnicity, gender, etc.); medical history; characteristics and timing of the infarction and diagnosis of cardiogenic shock; medications; interventions; adverse events; and hemodynamics closest to the time of CS, randomization, 6 hours after randomization, and 12 hours after randomization. Quality of life and physical function assessments were completed by telephone interview at 2 weeks after hospital discharge and 6 months after MI. A one-year post-MI interview was also conducted with trial patients randomly assigned before the last year of the enrollment period. All patients alive at their last contact had vital status assessed at trial termination. The primary end point was 30-day overall mortality; secondary end points were six- and 12-month survival after infarction, changes in echocardiography variables (measured using Doppler echocardiography), and changes in quality of life and physical functioning.
- Timeframe
- 1993 - 1998
- Geographic Coverage
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CanadaUnited States
- Local Expert
Access
- Restrictions
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Free to All
- Instructions
- De-identified data, codebooks, and case report forms are available on the Zenodo data repository.
- PubMed Search
- View articles which use this dataset
- Other Resources
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ClinicalTrials.gov
NCT00000552