Should We Emergently Revascularize Occluded Coronaries for Cardiogenic Shock Trial

Alternate Titles(s): SHOCK Trial
UID: 10724
Author(s): Judith S. Hochman*

* Corresponding Author
Description

This dataset contains information from the Should We Emergently Revascularize Occluded Coronaries for Cardiogenic Shock (SHOCK) study, a randomized controlled trial of 302 patients with cardiogenic shock (CS) due to acute myocardial infarction (MI); 175 were treated in the United States, 66 in Canada, and 61 in other countries. Data collected between April 1993 and November 1998 from 30 sites and were entered into a structured database housed at NERI (now Carelon Research).

Participants were randomly assigned to emergency revascularization or initial medical stabilization. Information was collected on all aspects of the patient and their hospital stay, including demographics (race, ethnicity, gender, etc.); medical history; characteristics and timing of the infarction and diagnosis of cardiogenic shock; medications; interventions; adverse events; and hemodynamics closest to the time of CS, randomization, 6 hours after randomization, and 12 hours after randomization. Quality of life and physical function assessments were completed by telephone interview at 2 weeks after hospital discharge and 6 months after MI. A one-year post-MI interview was also conducted with trial patients randomly assigned before the last year of the enrollment period. All patients alive at their last contact had vital status assessed at trial termination. The primary end point was 30-day overall mortality; secondary end points were six- and 12-month survival after infarction, changes in echocardiography variables (measured using Doppler echocardiography), and changes in quality of life and physical functioning.

Timeframe
1993 - 1998
Geographic Coverage
Canada
United States
Local Expert
Subject of Study
Subject Domain
Population Age
Adult (19 years - 64 years)
Senior (65 years - 79 years)
Aged (80 years and over)
Keywords

Access

Restrictions
Free to All
Instructions
De-identified data, codebooks, and case report forms are available on the Zenodo data repository.
Associated Publications
Data Type
Study Type
Interventional
Dataset Format(s)
CSV
Data Collection Instruments
Multidimensional Quality of Life Index
Sickness Impact Profile
Dataset Size
2.5 MB
PubMed Search
View articles which use this dataset
Other Resources
ClinicalTrials.gov

NCT00000552