This dataset was created as part of a prospective review of somatosensory evoked potential (SEP) recordings obtained during intraoperative monitoring (IOM) on instrumented spinal surgeries that were performed for chronic underlying neurologic and neuromuscular conditions, including scoliosis, myelopathy, and spinal stenosis, on patients who did not exhibit any postoperative neurologic deficits. For...

This dataset was compiled as part of a study to compare T1-T4 decrement between upper and lower extremity muscles as a way to investigate the difference between recovery time from a neuromuscular blocking agent (NMBA). The study analyzed the differences between recovery of the foot, abductor hallucis muscle, and hand, first dorsal interosseous muscle, by application of quantitative train-of-four (TOF)...

This dataset was compiled as part of the Graphic User Interface for deep brain stimulation (DBS) Evaluation (GUIDE) study, a multicenter prospective pilot study designed to assess whether a computer-guided model could provide equally effective and more expeditious programming results when compared with the traditional, clinical deduced method of DBS programming of the subthalamic nucleus (STN). 26...

In order to study the effects of deep brain stimulation (DBS) in cases of refractory Tourette syndrome (TS), researchers performed a retrospective chart review of patients who underwent surgery between January 2009 and May 2016. Thirteen consecutive patients with at least 6 months of follow-up are included in this dataset. Patients were assessed using the Yale Global Tic Severity Scale (YGTSS), and...

The Scientific Registry of Transplant Recipients (SRTR) database includes data collected by the Organ Procurement and Transplantation Network (OPTN), supplemented with data from the Centers for Medicare & Medicaid Services (CMS) and the National Technical Information Services (NTIS) Death Master File. The database allows organ transplant programs to register candidates for transplant, match donated...

This dataset was collected to show that there is a decline in cytotoxic T cells and TCR clonality in organ transplant recipients (OTRs) with squamous cell carcinoma (SCC). In this study, 5 SCC tumor samples and 6 transplant-associated SCC (TSCC) tumor samples were analyzed. Among SCC samples, the male to female ratio was 3 to 2 and the mean patient age was 81 years. Among TSCC samples, the male to...

Clinical data was extracted from electronic health records from patients treated for hip fractures by the Department of Orthopedic Surgery at NYU Langone Health between October 2014 and February 2020. A total of 1,590 patients aged 55 and older were included in the retrospective review with complete records for patient's sex; body mass index; comorbidities as measured with the Charlson Comorbidity...

Dopamine is a critical modulator of brain circuits that control voluntary movements. However, its influence on the activity of target neurons in vivo remains limited. In this study, two-photon microscopy was used to monitor the activity of direct and indirect-pathway spiny projection neurons (SPNs) simultaneously in the striatum of behaving mice. The striatum mainly consists of two large populations...

The dorsal root ganglia (DRG) are the first-order neurons in the somatosensory system. However, DRG neuronal activity in awake behaving animals remains unknown. This study developed a method for imaging DRG at cellular and subcellular resolution over weeks in awake mice. They installed an intervertebral fusion mount to reduce spinal movement and implanted a vertebral glass window without interfering...

This study identified the gut microbiome during an acute enteric infection in patients with and without inflammatory bowel disease (IBD). A cross-sectional study was performed on 260 patients who underwent stool testing and tested positive for Clostridioides difficile, Escherichia coli, or norovirus, or negative for all pathogens, and 25 healthy controls. They collected the following data from the...