Anti-DNA and Anti-Phosphatidylserine Antibodies Predicted Development of Severe COVID-19
- Description
This is a retrospective cohort study of COVID-19 hospitalized patients with different degrees of severity. They performed this study to analyze the generation of autoimmune antibodies to common antigens. This study included 115 hospitalized patients with SARS-CoV-2 infection and 42 uninfected controls. Sample collection was performed as part of routine clinical care for COVID-19 patients at the time of hospital admission. Assessment of SARS-CoV-2 infection was performed using nasopharyngeal swabs in clinical PCR assays. The dataset includes a summary of demographic and clinical characteristics of patients, correlation among autoantibody and immune complex levels, and correlation between autoantibodies and severity/living status of hospitalized patients. There are also data about levels of IgG autoimmune antibodies, anti-DNA antibodies from COVID-19 patients, autoantibody levels, levels of immune complex, and correlation analysis of autoantibodies.
- Timeframe
- 2020
- Geographic Coverage
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New York (State) - New York City
Access
- Restrictions
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Free to All
- Instructions
- De-identified data underlying manuscript figures are available for download through PubMed Central (PMC) under Supplementary Materials.
- Grant Support
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COVID-19 Special Fund/NYU Langone HealthCOVID-19 Response Initiative/Bloomberg Philanthropies