-
NYU Dataset
NYU Women's Health Study: Temporal Reproducibility of IgG and IgM Autoantibodies in Serum from Healthy Women
- Alternate Title(s)
- NYUWHS
- Authors
- Tess ClendenenShaohui HuYelena AfanasyevaManor Askenazi7 more author(s)...
- Description
Study investigators examined blood samples from participants in the NYU Women’s Health Study (NYUWHS)--a cohort of 14,274 women enrolled between 1985 and 1991 through a breast cancer screening center in New York City--to identify autoantibodies associated with healthy women. The blood samples were collected at the time of enrollment and at annual screening visits until 1991 and long term follow-up...
- Access Rights
- Free to All
-
NYU Dataset
Immune Responses Observed Before and After BNT162b2 mRNA Vaccine Administration in Individuals with and without History of SARS-CoV-2 Infection
- Authors
- Marie I. SamanovicAmber R. CorneliusSophie L. Gray-GaillardJoseph Richard Allen7 more author(s)...
- Description
To study and compare longitudinal immune responses to two-dose BNT162b2 mRNA vaccinations, investigators recruited 15 adults with a history of laboratory-confirmed COVID-19 and 21 adults who did not have COVID-19. Participants' ages ranged from 21 to 65 years old. Peripheral immune responses were assessed via blood samples drawn before and after each vaccine dose. A total of five samples were collected...
- Subject
-
COVID-19Infectious Disease
- Timeframe
- 2021
- Access Rights
- Free to All
-
NYU Dataset
Anti-DNA and Anti-Phosphatidylserine Antibodies Predicted Development of Severe COVID-19
- Authors
- Claudia GomesMarisol ZunigaKelly A. CrottyKun Qian11 more author(s)...
- Description
This is a retrospective cohort study of COVID-19 hospitalized patients with different degrees of severity. They performed this study to analyze the generation of autoimmune antibodies to common antigens. This study included 115 hospitalized patients with SARS-CoV-2 infection and 42 uninfected controls. Sample collection was performed as part of routine clinical care for COVID-19 patients at the time...
- Subject
-
COVID-19Infectious Disease
- Timeframe
- 2020
- Access Rights
- Free to All
-
NYU Dataset
Autoimmunity to Annexin A2 Predicts Mortality Among Hospitalised COVID-19 Patients
- Authors
- Marisol ZunigaClaudia GomesSteven E. CarsonsMichael T. Bender4 more author(s)...
- Description
This study examined autoimmune antibodies to annexin A2, which is a phospholipid-binding protein expressed in the lung and other organs, in COVID-19 patients. Annexin A2 is critical for fibrinolysis, lung elasticity, cell membrane repair, and integrity of the pulmonary vasculature. Therefore, antagonism of annexin A2 may explain many of the clinical features of severe COVID-19 cases. This study analyzed...
- Subject
-
COVID-19Infectious Disease
- Access Rights
- Application RequiredAuthor Approval Required
-
NYU Dataset
mRNA COVID-19 vaccine elicits potent adaptive immune response without the acute inflammation of SARS-CoV-2 infection
- Authors
- Ellie IvanovaJasmine ShwetarJoseph C. DevlinTerkild B. Buus17 more author(s)...
- Description
To investigate immune responses to SARS-CoV-2 antigens under various inflammatory conditions, researchers collected blood samples from five adult patients seen at NYU Langone Health with lab-confirmed cases of acute COVID-19 and from nine healthy adults (seven who had received the BNT162b2 mRNA vaccine and two with no prior exposure to SARS-CoV-2). Samples were obtained at multiple time points. Patients...
- Subject
-
COVID-19GenomicsInfectious Disease
- Access Rights
- Free to All
