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NYU Dataset
Protein Modifications Discovered Using Differential Tandem Mass Spectrometry Proteomics
- Authors
- Paolo CifaniZhi LiDanmeng LuoMark Grivainis3 more author(s)...
- Description
This dataset was collected to present a spectral alignment method for the identification of protein modifications using high-resolution mass spectrometry proteomics. For this study, they used SAMPEI for spectral alignment-based modified peptide identification. SAMPEI is an open-source algorithm that is designed for the discovery of functional protein and peptide signaling modifications. Human OCI-AML2...
- Subject
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GenomicsProteomics
- Access Rights
- Free to All
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NYU Dataset
Hypothalamic Melanin-Concentrating Hormone Regulates Hippocampus-Dorsolateral Septum Activity
- Authors
- Jing-Jing LiuRichard W. TsienZhiping P. Pang
- Description
Hypothalamic melanin-concentrating hormone (MCH) polypeptide contributes to regulating energy homeostasis, sleep, and memory. However, the mechanistic bases of its effects are still unclear. This study found that the physiological mechanism underlying the functional role of MCH signaling in projections to the dorsolateral septum (dLS), which is a region involved in routing hippocampal firing rhythms...
- Subject
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Neuroscience
- Access Rights
- Free to All
