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NYU Dataset
Perimenopause and emergence of an Alzheimer’s bioenergetic phenotype in brain and periphery
- Authors
- Lisa MosconiRussell H. SwerdlowMony de LeonRichard S. Isaacson9 more author(s)...
- Description
This data was generated in a study to characterize brain bioenergetics in a cohort of clinically and cognitively normal women between the ages of 40 and 50 at different endocrine transition states including premenopause (n = 15), perimenopause (n = 14), and postmenopause (n = 14) in order to study the increased risk for Alzheimer’s disease in women. All subjects received clinical, laboratory, and neuropsychological...
- Subject
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Chronic DiseaseNeuroscienceRisk Factors
- Access Rights
- Free to All
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Alzheimer’s Disease Neuroimaging Initiative
- Alternate Title(s)
- ADNI, ADNI1, ADNI GO, ADNI2, ADNI3
- Authors
- Michael W. Weiner
- Description
The Alzheimer’s Disease Neuroimaging Initiative (ADNI) began in 2004 as longitudinal multicenter study to identify clinical, imaging, genetic, and biochemical biomarkers for the detection and tracking of Alzheimer’s disease (AD). Participants are recruited from and followed at 59 research sites in the United States and Canada. ADNI1 enrolled 400 subjects who were diagnosed with mild cognitive impairment...
- Subject
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Chronic DiseaseGenomicsMental HealthNeuroscience
- Access Rights
- Free to AllApplication RequiredAuthor Approval Required
- Local Expert
- Omonigho M. BubuRicardo Osorio
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National Alzheimer’s Coordinating Center Data
- Alternate Title(s)
- NACC
- Description
The National Alzheimer’s Coordinating Center (NACC) was created in 1999 to facilitate research with data collected from Alzheimer's Disease Research Centers (ADRCs) across the United States. NACC oversees data collection and sharing for a number of datasets. The Uniform Data Set (UDS) contains longitudinal and standardized data collected from ADRCs since 2005. ADRC enrollment protocols vary and...
- Subject
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Chronic DiseaseMental HealthNeuroscience
- Access Rights
- Free to AllApplication RequiredAuthor Approval Required
- Local Expert
- Omonigho M. BubuRicardo Osorio
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Cerebral Expression of Metabotropic Glutamate Receptor Subtype 5 in Idiopathic Autism Spectrum Disorder and Fragile X Syndrome
- Authors
- James Robert BrasicAyon NandiDavid S. RussellDanna Jennings7 more author(s)...
- Description
Prior studies have linked dysfunction of metabotropic glutamate receptors (mGluR) to idiopathic autism spectrum disorder (IASD) and fragile X syndrome (FXS). In this study, the investigators evaluated mGluR5 expression in participants with IASD, FXS, and typical development (TD) using positron emission tomography (PET). The Institute for Neurodegenerative Disorders (IND) in New Haven, Connecticut enrolled...
- Subject
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Neuroscience
- Access Rights
- Free to All
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Diagnostics, Imaging, and Genetics Network for the Objective Study and Evaluation of Chronic Traumatic Encephalopathy Research Project
- Alternate Title(s)
- DIAGNOSE CTE
- Authors
- Robert A. SternJeffrey CummingsEric M. ReimanMartha Shenton
- Description
Diagnostics, Imaging, and Genetics Network for the Objective Study and Evaluation of Chronic Traumatic Encephalopathy (DIAGNOSE CTE) was a longitudinal multi-site study of diagnostic methods for CTE and potential risk factors for the disease. The primary objectives of the study are to collect and analyze neuroimaging and fluid biomarkers for the detection of CTE during life, characterize its clinical...
- Subject
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Chronic DiseaseGenomicsMental HealthNeuroscienceRisk Factors
- Access Rights
- Application RequiredAuthor Approval Required
- Local Expert
- Hector Arciniega
