NYU Data Catalog

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  • NYU Dataset

    Lymphatic Vessels Limits the Intratumoral T cell Repertoire in Melanoma

    Authors
    Maria M. Steele
    Ian D. Dryg
    Dhaarini Murugan
    Julia Femel
    6 more author(s)...
    Description

    CD8+ T cell accumulation in tumors is essential for effective immunotherapy. However, the mechanisms of lymphocyte transit are still unclear. This study examined lymphatic vessel-mediated effector CD8+ T cell exit limits the accumulation of a broad repertoire of functional CD8+ T cells that improve tumor control in combination with immune checkpoint blockade. They showed that tumor-associated lymphatic...

    Subject
    Cancer
    Genomics
    Access Rights
    Application Required
    Author Approval Required
  • NYU Dataset

    Melanoma Clinicopathological-Biospecimen Database and Repository

    Authors
    Iman Osman
    Description

    Since 2002, the Interdisciplinary Melanoma Cooperative Group (IMCG) at Perlmutter Cancer Center has maintained one of the largest clinicopathologic resources, the Melanoma Clinicopathological-Biospecimen Database and Repository, for research on patients 18 years old and over with melanoma or at high risk for melanoma. Clinical data is stored in a secure REDCap database which contains 653 fields to...

    Subject
    Cancer
    Chronic Disease
    Genomics
    Risk Factors
    Access Rights
    Application Required
    Author Approval Required
  • NYU Dataset

    mRNA COVID-19 vaccine elicits potent adaptive immune response without the acute inflammation of SARS-CoV-2 infection

    Authors
    Ellie Ivanova
    Jasmine Shwetar
    Joseph C. Devlin
    Terkild B. Buus
    17 more author(s)...
    Description

    To investigate immune responses to SARS-CoV-2 antigens under various inflammatory conditions, researchers collected blood samples from five adult patients seen at NYU Langone Health with lab-confirmed cases of acute COVID-19 and from nine healthy adults (seven who had received the BNT162b2 mRNA vaccine and two with no prior exposure to SARS-CoV-2). Samples were obtained at multiple time points. Patients...

    Subject
    COVID-19
    Genomics
    Infectious Disease
    Access Rights
    Free to All