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  • NYU Dataset

    Acetyl-L-Carnitine Deficiency in Patients with Major Depressive Disorder

    Authors
    Carla Nasca
    Benedetta Bigio
    Francis S. Lee
    Sarah P. Young
    9 more author(s)...
    Description

    This study identified biological targets in major depressive disorder (MDD). Acetyl-l-carnitine (LAC), which is critical for hippocampal function and several behavioral domains, has rapid and enduring antidepressant like effects in LAC deficient rodents. As a result, this study examined LAC levels in humans. Following an initial phone screen, potential participants were evaluated in person to determine...

    Subject
    Neuroscience
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  • NYU Dataset

    GABA Decrease is Associated With Degraded Neural Specificity in the Visual Cortex of Glaucoma Patients

    Authors
    Ji Won Bang
    Carlos Parra
    Kevin Yu
    Gadi Wollstein
    2 more author(s)...
    Description

    To investigate the GABAergic and glutamatergic systems and neural specificity in the visual cortex of glaucoma patients, the research team recruited 40 patients with glaucoma (14 with early glaucoma and 16 with advanced glaucoma) and 24 age-matched healthy subjects to undergo clinical ophthalmic exams and magnetic resonance imaging (MRI) with fixation tasks. Researchers obtained the following data: Structural...

    Subject
    Anatomy
    Chronic Disease
    Neuroscience
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