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  • NYU Dataset

    DIAPH1 Mediates Progression of Atherosclerosis and Regulates Hepatic Lipid Metabolism in Mice

    Authors
    Laura Senatus
    Lander Egana-Gorrono
    Raquel Lopez-Diez
    Sonia Bergaya
    17 more author(s)...
    Description

    Previous study indicated that the receptor for advanced glycation end products (RAGE) in the progression and regression of atherosclerosis. Therefore, this study examined if Diaphanous 1 (DIAPH1) binds to the RAGE cytoplasmic domain and contributes to progression of atherosclerosis. They intercrossed atherosclerosis prone Ldlr−/− mice with mice devoid of Diaph1 and fed them Western diet for 16 weeks....

    Subject
    Genomics
    Access Rights
    Free to All