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  • NYU Dataset

    Gene Expression and Transcription Factors are Modified in Human Keratinocytes Exposed to Solar Simulated Ultraviolet Radiation

    Authors
    Thomas L. Des Marais
    Thomas Kluz
    Dazhong Xu
    Xiaoru Zhang
    4 more author(s)...
    Description

    Ultraviolet radiation (UVR) from the sun is the major cause of skin cancer. However, genes and pathways altered by solar-simulated UVR (ssUVR), a mixture of UVA and UVB, still remains unclear. For this study, human HaCaT keratinocytes were exposed to a single dose or 5 repetitive doses of ssUVR. Analyses of gene expression profiles and functional annotation were performed at 24 hours after irradiation....

    Subject
    Cancer
    Genomics
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