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  • NYU Dataset

    FITM2 Deficiency Promotes Hepatic ER Stress in Vitro and in Vivo

    Authors
    Haizhen Wang
    Cyrus Nikain
    Konstantinos I. Fortounas
    Jaume Amengual
    14 more author(s)...
    Description

    This study examined the role of hepatic FITM2, an endoplasmic reticulum (ER) protein, in the partitioning of newly-synthesized triglyceride between the ER, lipid droplets, and nascent very low density lipoprotein (VLDL) particles in vitro and in vivo. The experiments were conducted using a rat hepatic cell line (McA cells) and mice. Effects of FITM2 deficiency on VLDL assembly and secretion in vitro...

    Subject
    Proteomics
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