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NYU Dataset
Sequencing Data Illustrates Polyadenylation of Histone H3.1 mRNA Promotes Cell Transformation by Displacing H3.3 from Gene Regulatory Elements
- Authors
- Danqi ChenQiao Yi ChenZhenjia WangYusha Zhu12 more author(s)...
- Description
Previous study showed that exposure to arsenic, an environmental carcinogen, induces polyadenylation of canonical histone H3.1 mRNA. This study revealed that polyadenylation of H3.1 mRNA increases H3.1 protein, which results in displacement of histone variant H3.3 at active promoters, enhancers, and insulator regions. To investigate global changes in transcription induced by ectopic expression of polyadenylated...
- Subject
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Genomics
- Access Rights
- Free to All
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NYU Dataset
An Assessment of the Ocular Toxicity of Two Major Sources of Environmental Exposure
- Authors
- Steven H. RauchmanLora J. KasselmanAnkita SrivastavaJoshua De Leon1 more author(s)...
- Description
These data contain information on chemicals released in to the air from burn pits in Iraq (waste disposal areas for US military bases) and the 2023 Ohio train derailment in East Palestine. The goals of the study were to 1) predict the effects of exposure to these chemicals on the ocular surface and 2) to call attention to the relationship between environmental events and long-term damage to the surface...
- Subject
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Risk Factors
- Access Rights
- Free to All
