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  • NYU Dataset

    Ca2+ Channel ORAI1 Regulates Oral Cancer Growth and Nociceptive Pain

    Authors
    Ga-Yeon Son
    Nguyen Huu Tu
    Maria Daniela Santi
    Santiago Loya Lopez
    9 more author(s)...
    Description

    This study described the function of the Ca2+ channel ORAI1 as an important regulator of oral cancer pain. Previous study showed that ORAI1 was highly expressed in tumor samples from patients with oral cancer. ORAI1 activation caused sustained Ca2+ influx in human oral cancer cells. To address the effects of ORAI1 in cell proliferation, HSC-3 cells were stimulated with 25 µM cyclopiazonic acid in the...

    Subject
    Cancer
    Genomics
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