-
NYU Dataset
Targeting Succinate Receptor Effectively Inhibits Periodontal Disease
- Authors
- Yuqi GuoFangxi XuScott C. ThomasYanli Zhang10 more author(s)...
- Description
Periodontal disease (PD) is induced by a bacterial dysbiosis in the oral cavity that stimulates inflammation and bone loss. This study showed elevation of succinate in PD, which aggravates the disease through the succinate receptor (SUCNR1). Targeted metabolomic analysis was performed to compare the succinate level in the subgingival plaque of patients with mild or severe periodontitis, where 28 gingival...
- Subject
-
Genomics
- Access Rights
- Free to All