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  • NYU Dataset

    RNA Sequencing Analysis of Caenorhabditis elegans DAF-18 During Primordial Germ Cell Quiescence

    Authors
    Amanda L. Fry
    Amy K. Webster
    Julia Burnett
    Rojin Chitrakar
    2 more author(s)...
    Description

    PTEN is one of the most frequently lost tumor suppressors in human cancers and regulates quiescence of stem cells and cancer cells. The Caenorhabditis elegans daf-18 gene encodes the worm version of PTEN. Previous studies showed that in worms that have lost daf-18 function, primordial germ cells (PGCs) inappropriately begin dividing in the L1 larvae hatched into starvation conditions. This study examined...

    Subject
    Genomics
    Access Rights
    Free to All