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NYU Dataset
RNA and TCR Sequencing Characterized Cytotoxic T Cells and TCR Clonality in Organ Transplant Recipients with Squamous Cell Carcinoma
- Authors
- Nicholas FrazzetteAlireza Khodadadi-JamayranNicole DoudicanAlexis Santana4 more author(s)...
- Description
This dataset was collected to show that there is a decline in cytotoxic T cells and TCR clonality in organ transplant recipients (OTRs) with squamous cell carcinoma (SCC). In this study, 5 SCC tumor samples and 6 transplant-associated SCC (TSCC) tumor samples were analyzed. Among SCC samples, the male to female ratio was 3 to 2 and the mean patient age was 81 years. Among TSCC samples, the male to...
- Subject
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CancerGenomicsSurgery
- Access Rights
- Free to All
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NYU Dataset
Ca2+ Channel ORAI1 Regulates Oral Cancer Growth and Nociceptive Pain
- Authors
- Ga-Yeon SonNguyen Huu TuMaria Daniela SantiSantiago Loya Lopez9 more author(s)...
- Description
This study described the function of the Ca2+ channel ORAI1 as an important regulator of oral cancer pain. Previous study showed that ORAI1 was highly expressed in tumor samples from patients with oral cancer. ORAI1 activation caused sustained Ca2+ influx in human oral cancer cells. They analyzed the expression of ORAI1 in the human oral squamous cell carcinoma cell lines HSC-3 and SCC-9, in the dysplastic...
- Subject
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CancerGenomics
- Access Rights
- Free to All