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  • NYU Dataset

    RNA and TCR Sequencing Characterized Cytotoxic T Cells and TCR Clonality in Organ Transplant Recipients with Squamous Cell Carcinoma

    Authors
    Nicholas Frazzette
    Alireza Khodadadi-Jamayran
    Nicole Doudican
    Alexis Santana
    4 more author(s)...
    Description

    This dataset was collected to show that there is a decline in cytotoxic T cells and TCR clonality in organ transplant recipients (OTRs) with squamous cell carcinoma (SCC). In this study, 5 SCC tumor samples and 6 transplant-associated SCC (TSCC) tumor samples were analyzed. Among SCC samples, the male to female ratio was 3 to 2 and the mean patient age was 81 years. Among TSCC samples, the male to...

    Subject
    Cancer
    Genomics
    Surgery
    Access Rights
    Free to All
  • NYU Dataset

    Ca2+ Channel ORAI1 Regulates Oral Cancer Growth and Nociceptive Pain

    Authors
    Ga-Yeon Son
    Nguyen Huu Tu
    Maria Daniela Santi
    Santiago Loya Lopez
    9 more author(s)...
    Description

    This study described the function of the Ca2+ channel ORAI1 as an important regulator of oral cancer pain. Previous study showed that ORAI1 was highly expressed in tumor samples from patients with oral cancer. ORAI1 activation caused sustained Ca2+ influx in human oral cancer cells. They analyzed the expression of ORAI1 in the human oral squamous cell carcinoma cell lines HSC-3 and SCC-9, in the dysplastic...

    Subject
    Cancer
    Genomics
    Access Rights
    Free to All