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  • NYU Dataset

    Proteogenomic Analysis of Cancer Aneuploidy and Normal Tissues

    Authors
    Pan Cheng
    Xin Zhao
    Lizabeth Katsnelson
    Elaine M. Camacho-Hernandez
    9 more author(s)...
    Description

    This study performed a proteogenomic analysis of DNA, RNA and protein levels across primary tumor samples and cancer cell lines from different tumor types, a panel of isogenic non-tumorigenic human colon epithelial cells and normal tissues. They found tissue specificity in the RNA-level and protein-level compensation of genes are affected by somatic copy number alterations (SCNAs). Using the DNA–RNA...

    Subject
    Cancer
    Genomics
    Proteomics
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