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  • NYU Dataset

    Video and single cell recordings from a study of the role of oxytocin neurons in social transmission of maternal behavior among mice

    Authors
    Ioana Carcea
    Robert C. Froemke
    Description

    Oxytocin, a hormone released by the hypothalamic paraventricular nucleus (PVN), enables neuroplasticity in the auditory cortex for maternal recognition of pup distress. This study continuously monitored the behavior of female virgin mice co-housed with an experienced mother and litter. To examine the behavioral events and neural activity patterns that lead to maternal behavior in virgin female mice,...

    Subject
    Neuroscience
    Access Rights
    Free to All
  • NYU Dataset

    Infant pain vs. pain with parental suppression: Immediate and enduring impact on brain, pain and affect

    Authors
    Gordon A. Barr
    Maya Opendak
    Rosemarie E. Perry
    Emma Sarro
    1 more author(s)...
    Description

    To investigate the impact of social buffering on pain, the study team administered mild tail shocks to infant rat pups at postnatal day (PN) 8 or 12, with or without their mothers. They hypothesized that repeated exposure to shock would alter their inflammatory pain responses as adults when experienced between PN5 and 9 (pain sensitive period prior to functional maturation of the amygdala), whereas...

    Subject
    Mental Health
    Neuroscience
    Access Rights
    Free to All