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Osteoarthritis Initiative
- Alternate Title(s)
- OAI
- Description
The Osteoarthritis Initiative (OAI) was a longitudinal cohort study which investigated the natural history of knee osteoarthritis across the spectrum of the disease through the collection of imaging, biochemical, genetic, and risk markers of knee OA. Measures included knee symptoms and function (evaluated using the West Ontario and McMaster Universities Arthritis Index (WOMAC) and the Knee injury and...
- Subject
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Chronic DiseaseHealth StatusRisk Factors
- Access Rights
- Free to AllApplication Required
- Local Expert
- Cem DenizJonathan Samuels
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Multicenter Osteoarthritis Study
- Alternate Title(s)
- MOST
- Authors
- Neil A. SegalMichael C. NevittK. Douglas GrossJean Hietpas3 more author(s)...
- Description
The Multicenter Osteoarthritis Study (MOST) is an ongoing longitudinal study which aims to identify novel and modifiable biomechanical factors (e.g., physical activity), bone and joint structural factors (assessed through knee MRI), and nutritional factors that are associated with the onset and progression of osteoarthritis (OA)-related knee symptoms and radiographic knee OA. A secondary aim is to...
- Subject
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Chronic DiseaseRisk Factors
- Access Rights
- Application RequiredAuthor Approval Required
- Local Expert
- Cem Deniz
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NYU Dataset
Peripheral Blood Leukocytes Gene Expression Predicts Risk for Progression of Symptomatic Knee Osteoarthritis
- Authors
- Mukundan AtturIlana Belitskaya-LevyCheongeun OhSvetlana Krasnokutsky9 more author(s)...
- Description
This study investigated gene expression profiles in peripheral blood leukocytes of patients with osteoarthritis (OA) in comparison with non-OA controls to evaluate whether gene expression profiles could serve as biomarkers of symptomatic knee OA. Three cohorts were studied: two cohorts (learning cohort and validation cohort) recruited at New York University Hospital for Joint Diseases (NYUHJD) and...
- Subject
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Genomics
- Access Rights
- Free to All
