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  • NYU Dataset

    Proper Mitochondrial Translation Initiation and Maintenance of Formylmethionyl tRNAs Requires SHMT2

    Authors
    Denise R. Minton
    Minwoo Nam
    Daniel J. McLaughlin
    Jong Shin
    7 more author(s)...
    Description

    Eukaryotic cells upregulate oxidative metabolism to maintain homeostasis upon glucose restriction. This study used CRISPR/Cas9-based screening to identify serine catabolic enzyme SHMT2. They found that the mitochondrial SHMT2 is required for robust mitochondrial oxygen consumption and low glucose proliferation. This dataset contains immunoblot images, as well as supplementary data tied to the publication....

    Subject
    Genomics
    Access Rights
    Free to All