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NYU Dataset
Proper Mitochondrial Translation Initiation and Maintenance of Formylmethionyl tRNAs Requires SHMT2
- Authors
- Denise R. MintonMinwoo NamDaniel J. McLaughlinJong Shin7 more author(s)...
- Description
Eukaryotic cells upregulate oxidative metabolism to maintain homeostasis upon glucose restriction. This study used CRISPR/Cas9-based screening to identify serine catabolic enzyme SHMT2. They found that the mitochondrial SHMT2 is required for robust mitochondrial oxygen consumption and low glucose proliferation. This dataset contains immunoblot images, as well as supplementary data tied to the publication....
- Subject
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Genomics
- Access Rights
- Free to All