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NYU Dataset
Predictors of Neuritic Plaque and Neurofibrillary Tangle Pathology Determined From Rush Religious Orders Study
- Authors
- Stephen D. GinsbergMichael H. Malek-AhmadiMelissa J. AlldredYinghua Chen4 more author(s)...
- Description
This study investigated whether the Alzheimer’s disease (AD) pathological lesions diffuse plaques (DPs), neuritic plaques (NPs), and neurofibrillary tangles (NFTs). Negative binomial regressions was performed using gene expression data accrued from a single population of CA1 pyramidal neurons and regional hippocampal dissections obtained from participants in the Rush Religious Orders Study (RROS)....
- Subject
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GenomicsNeuroscience
- Access Rights
- Application RequiredAuthor Approval Required
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NYU Dataset
Selective Decline of Neurotrophin and Neurotrophin Receptor Genes Discovered From Rush Religious Orders Study
- Authors
- Stephen D. GinsbergMichael H. Malek-AhmadiMelissa J. AlldredShaoli Che7 more author(s)...
- Description
This study profiled neurotrophin and neurotrophin receptor gene expression within microdissected CA1 neurons along with regional hippocampal dissections from participants in the Rush Religious Orders Study (RROS). The RROS participants included older religious clergy who have agreed to medical and psychological evaluation each year and brain donation after death. This study began in 1993 and has enrolled...
- Subject
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GenomicsNeuroscience
- Access Rights
- Application RequiredAuthor Approval Required