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NYU Dataset
Hierarchical Representations of Aggression in a Hypothalamic-Midbrain Circuit
- Authors
- Annegret L. FalknerDongyu WeiAnjeli SongLi W. Watsek4 more author(s)...
- Description
Ventrolateral area is known as a critical locus for the generation of conspecific aggression, where neurons responding during multiple phases of a social interaction. However, how these neurons organize aggressive action is still unknown. This study found that a hypothalamic-midbrain circuit that represents hierarchically organized signals during aggression. For this study, C57BL/6N, Swiss Webster,...
- Subject
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Neurosciences
- Access Rights
- Application RequiredAuthor Approval Required
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NYU Dataset
Inhibitory Co-Transmission From Midbrain Dopamine Neurons Relies on Presynaptic GABA Uptake
- Authors
- Riccardo MelaniNicolas X. Tritsch
- Description
Dopamine-releasing neurons in the substantia nigra pars compacta inhibit target cells in the striatum through postsynaptic activation of γ-aminobutyric acid (GABA) receptors. However, the molecular mechanisms responsible for GABAergic signaling remains unknown. This study demonstrated that dopamine-releasing substantia nigra pars compacta neurons do not produce GABA using Aldh1a1 but rely instead on...
- Subject
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Neurosciences
- Access Rights
- Free to All
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NYU Dataset
Identifying Behavioral Links to Neural Dynamics of Multifiber Photometry Recordings
- Authors
- Yibo ChenJonathan ChienBing DaiDayu Lin1 more author(s)...
- Description
The hypothalamic-midbrain neural circuits play an important role in social interactions involving aggression, defense, and mating. However, how population-averaged neural activity measured by multi-fiber photometry (MFP) for calcium fluorescence signals correlates with social behaviors is a fundamental question. This study proposed a state-space analysis framework to characterize mouse MFP data based...
- Subject
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Neurosciences
- Access Rights
- Free to All