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NYU Dataset
3D Reconstructions of Parasite Development and the Intracellular Niche of Encephalitozoon intestinalis
- Authors
- Noelle V. AntaoCherry LamAri DavydovMargot Riggi6 more author(s)...
- Description
Microsporidia are obligate intracellular pathogens that infect a wide range of invertebrate and vertebrate hosts, including humans. In humans, microsporidia most often infect the gastrointestinal tract and cause diarrheal diseases, but in immunocompromised patients, infections can be fatal. Previous knowledge of microsporidian intracellular development was based on 2D transmission electron microscopy...
- Subject
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Infectious Disease
- Access Rights
- Free to All
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NYU Dataset
Energetics of the Microsporidian Polar Tube Invasion Machinery
- Authors
- Ray ChangAri DavydovPattana JaroenlakBreane Budaitis3 more author(s)...
- Description
Microsporidia are obligate intracellular parasites that use an unusual invasion organelle called the polar tube (PT), which is ejected from a dormant spore at ultra-fast speeds, to infect host cells. This study used serial block-face scanning electron microscopy (SBF-SEM) to capture 3-dimensional snapshots of Anncaliia algerae spores in different states of the PT ejection process. They proposed a theoretical...
- Subject
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Infectious Disease
- Access Rights
- Free to All
