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  • NYU Dataset

    High-Resolution Fluorescence-Guided Transcranial Ultrasound Mapping in the Live Mouse Brain

    Authors
    Hector Estrada
    Justine Robin
    Ali Ozbek
    Zhenyue Chen
    7 more author(s)...
    Description

    Studying the physiological impact of transcranial ultrasound in rodent brains may offer an important preclinical model for human scale magnetic resonance-guided focused ultrasound methods. Therefore, this study found a versatile bidirectional hybrid fluorescence-ultrasound system with a fiberscope-based wide-field fluorescence imaging. This dataset contains functional connectivity data. The functional...

    Subject
    Neuroscience
    Access Rights
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  • NYU Dataset

    Forty-Hertz Light Stimulation Does Not Entrain Native Gamma Oscillations in Alzheimer’s Disease

    Authors
    Marisol Soula
    Alejandro Martin-Avila
    Yiyao Zhang
    Annika Dhingra
    4 more author(s)...
    Description

    Alzheimer’s disease (AD) is characterized by abnormal aggregation of the proteins amyloid-β (Aβ). Recent studies showed that 40-Hz sensory stimulation is a potential treatment in AD. This study examined whether 40-Hz flickering light entrains gamma oscillations and suppresses Aβ in the brains of APP/PS1 and 5xFAD mouse models. For the study, they investigated the effect of 40-Hz light stimulation on...

    Subject
    Neuroscience
    Access Rights
    Free to All