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NYU Dataset
High-Resolution Fluorescence-Guided Transcranial Ultrasound Mapping in the Live Mouse Brain
- Authors
- Hector EstradaJustine RobinAli OzbekZhenyue Chen7 more author(s)...
- Description
Studying the physiological impact of transcranial ultrasound in rodent brains may offer an important preclinical model for human scale magnetic resonance-guided focused ultrasound methods. Therefore, this study found a versatile bidirectional hybrid fluorescence-ultrasound system with a fiberscope-based wide-field fluorescence imaging. This dataset contains functional connectivity data. The functional...
- Subject
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Neuroscience
- Access Rights
- Free to All
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NYU Dataset
Forty-Hertz Light Stimulation Does Not Entrain Native Gamma Oscillations in Alzheimer’s Disease
- Authors
- Marisol SoulaAlejandro Martin-AvilaYiyao ZhangAnnika Dhingra4 more author(s)...
- Description
Alzheimer’s disease (AD) is characterized by abnormal aggregation of the proteins amyloid-β (Aβ). Recent studies showed that 40-Hz sensory stimulation is a potential treatment in AD. This study examined whether 40-Hz flickering light entrains gamma oscillations and suppresses Aβ in the brains of APP/PS1 and 5xFAD mouse models. For the study, they investigated the effect of 40-Hz light stimulation on...
- Subject
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Neuroscience
- Access Rights
- Free to All
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NYU Dataset
Oxytocin Attenuates Microglial Activation and Restores Social and Non-Social Memory in APP/PS1 Mice
- Authors
- Maria Clara SellesJuliana T.S. FortunaYasmin P.R. de FariaLuciana Domett Siqueira5 more author(s)...
- Description
This study examined oxytocin expression in experimental models of Alzheimer’s disease (AD), and evaluated the therapeutic potential of treatment with oxytocin. They investigated changes in oxytocin expression in APP/PS1 mouse model and developed a chronic intranasal treatment protocol to increase oxytocin levels in the brain. Then, tested oxytocin as a potential approach to attenuate microglial activation...
- Subject
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Neuroscience
- Access Rights
- Free to All