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NYU Dataset
Immunotherapy Efficacy in Melanoma is Modulated by Gut Microbiota
- Authors
- Brandilyn A. PetersMelissa WilsonUna MoranAnna Pavlick5 more author(s)...
- Description
This study characterized gut microbiome in pre-treatment stool using 16S rRNA gene and shotgun metagenome sequencing in melanoma patients undergoing immunotherapy. Transcriptional expression of metagenomic pathways was confirmed with metatranscriptome sequencing. Metatranscriptomics is important for determining expression of metagenomic functions in the microbial community. They also examined associations...
- Subject
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Genomics
- Access Rights
- Free to All
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NYU Dataset
Gut microbiome dysbiosis in antibiotic-treated COVID-19 patients is associated with microbial translocation and bacteremia
- Authors
- Lucie Bernard-RaichonMericien VenzonJon KleinJordan E. Axelrad21 more author(s)...
- Description
To investigate the relationship between gut microbiome dysbiosis and translocation of bacteria into the blood during SARS-CoV-2 infection in humans, researchers obtained blood culture and stool samples from positive COVID-19 patients who were seen at NYU Langone Health and Yale New Haven Hospital. 67 stool samples were obtained from 60 patients at NYU Langone Health and 63 samples were obtained from...
- Subject
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COVID-19GenomicsInfectious DiseaseRisk Factors
- Timeframe
- 2020
- Access Rights
- Free to All
