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  • NYU Dataset

    NR2F2 Isoform Unleashes a Metastatic Program in Melanoma

    Authors
    Veronica Davalos
    Claudia D. Lovell
    Richard Von Itter
    Igor Dolgalev
    17 more author(s)...
    Description

    This study described DNA methylation changes that accompany metastatic progression in melanoma patients and found localized methylation changes in the regulatory region of NR2F2. NR2F2 is an orphan-nuclear receptor that is essential for embryonic and neural crest cell (NCC) development. For this study, they examined DNA methylation profiles of NCCs and melanocytes as well as melanoma patient tissues...

    Subject
    Cancer
    Genomics
    Access Rights
    Free to All